Evaluation of abnormal liver function tests

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Evaluation of abnormal liver function tests

Interpretation of abnormalities in liver function tests is a common problem faced by clinicians. This has become more common with the introduction of automated routine laboratory testing. Not all persons with one or more abnormalities in these tests actually have liver disease. The various biochemical tests, their pathophysiology, and an approach to the interpretation of abnormal liver function...

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Evaluation of abnormal liver function tests.

Although the liver can be affected in a wide range of disorders, the differential diagnosis of abnormal liver function tests can be substantially narrowed by a comprehensive history and physical examination and by the recognition of relatively distinct biochemical patterns of liver injury. Although referral to a specialist may be required for the performance of, for example, percutaneous liver ...

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Abnormal Liver Function Tests

LFTs are not specific to specific systems or disease processes, yet abnormalities may indicate significant or serious disease. Interpreting abnormal LFTs and trying to diagnose any underlying liver disease is a common scenario in Primary Care. Single abnormalities in LFTs are difficult to localise and diagnose [2] . However, the pattern of abnormalities tests helps determine origin of the issue...

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Abnormal Liver Function Tests:

Serum levels of aspartate aminotransferase and alanine aminotransferase that exceed 1000 IU/L indicate acute viral hepatitis (A, B and, rarely, C), acute drug toxicity (eg, acetaminophen overdose or isoniazid hepatotoxicity), or ischemic liver injury. In chronic hepatitis (ie, hepatitis B or C or autoimmune), values range from mildly elevated to usually less than 400 IU/L. Elevated levels of al...

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Evaluation of abnormal liver tests.

Serum liver tests are important but often problematic in evaluating patients with and without symptoms of hepatic disease. The common term "liver function tests" is misleading because most tests used in clinical practice measure hepatocellular damage not function. True liver function tests are those that measure synthesis of proteins made by the liver (albumin, clotting factors) or the liver's ...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 2016

ISSN: 0032-5473,1469-0756

DOI: 10.1136/postgradmedj-2015-133715